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KMID : 0366919930050010034
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Sungkyun Pharmceutical Journal
1993 Volume.5 No. 1 p.34 ~ p.38
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The Antihypertensive Effects of New Ca^2+ Channel Blockers
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Abstract
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Diltiazem and nifedipine, have been used throughout the world as an effective antianginal and antihypertensive agent. In order to increase the activity of these drugs, we synthesized the diltiazem-nifedipine coupling compounds. These compounds^(1-8) were tested for antihypertensive effect. Unfortunately, these compounds didn´t show any promising activities.
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